Ua hāʻawi ʻia ʻo Endre Mester, he kauka Hungarian, a he kauka ʻokiʻoki, i ka ʻike ʻana i nā hopena olaola o nā lasers mana haʻahaʻa, i hana ʻia i kekahi mau makahiki ma hope o ka hana ʻia ʻana o ka laser ruby i ka makahiki 1960 a me ka hana ʻia ʻana o ka laser helium-neon (HeNe) i ka makahiki 1961.
Ua hoʻokumu ʻo Mester i ke Kikowaena Noiʻi Laser ma ke Kulanui Lapaʻau ʻo Semmelweis ma Budapest i ka makahiki 1974 a ua hoʻomau i ka hana ma laila no ke koena o kona ola. Ua hoʻomau kāna mau keiki i kāna hana a lawe mai iā ia i ʻAmelika Hui Pū ʻIa.
I ka makahiki 1987, ua ʻōlelo nā ʻoihana e kūʻai aku ana i nā lasers hiki iā lākou ke mālama i ka ʻeha, hoʻolalelale i ka ho'ōla ʻana i nā ʻeha haʻuki, a me nā mea hou aku, akā he kakaikahi nā hōʻike no kēia i kēlā manawa.
Ua kapa mua ʻo Mester i kēia ʻano hana he "laser biostimulation", akā ua kapa koke ʻia ʻo "low-level laser therapy" a i ʻole "red light therapy". Me nā diode hoʻomālamalama i hoʻololi ʻia e ka poʻe e aʻo ana i kēia ʻano hana, ua kapa ʻia ʻo "low-level light therapy", a no ka hoʻoponopono ʻana i ka huikau e pili ana i ke ʻano pololei o "low level", ua kū mai ka huaʻōlelo "photobiomodulation".