ʻO ke kukui ma nā ʻaoʻao ʻulaʻula a kokoke i ka infrared o ke spectrum e hoʻolalelale i ka ho'ōla ʻana i nā pūnaewele a me nā ʻiʻo āpau. ʻO kekahi o nā ala a lākou e hoʻokō ai i kēia, ʻo ia ka hana ʻana ma ke ʻano he antioxidants ikaika. Hoʻopaʻa pū lākou i ka hana ʻana o ka nitric oxide.
Hiki i ke kukui ʻulaʻula a me ke kukui kokoke-infrared ke pale a hoʻohuli paha i ka nalowale o ka lohe?
Ma kahi noiʻi i ka makahiki 2016, ua hoʻopili nā kānaka noiʻi i ke kukui kokoke i ka infrared i nā cell auditory in vitro ma mua o ke kau ʻana iā lākou ma lalo o ke kaumaha oxidative ma ka hōʻike ʻana iā lākou i nā ʻano lāʻau make like ʻole. Ma hope o ka hōʻike ʻana i nā cell i hoʻomaʻamaʻa mua ʻia i ka lāʻau make chemotherapy a me ka endotoxin, ua ʻike nā kānaka noiʻi noiʻi ua hoʻololi ke kukui i ka metabolism mitochondrial a me ka pane kaumaha oxidative a hiki i 24 mau hola ma hope o ka mālama ʻana.
"Ke hōʻike nei mākou i ka emi ʻana o nā cytokines mumū a me nā pae kaumaha ma muli o ka NIR i hoʻopili ʻia i nā pūnaewele auditory HEI-OC1 ma mua o ka mālama ʻana me gentamicin a i ʻole lipopolysaccharide," i kākau ai nā mea kākau noiʻi.
Ua hōʻike ʻia nā hopena o ke aʻo ʻana ua hōʻemi ka mālama mua ʻana me ke kukui kokoke i ka infrared i nā māka pro-inflammatory e pili ana me ka hoʻonui ʻia o nā ʻano oxygen reactive a me ka nitric oxide.
Haʻawina #1: Hiki i ke kukui ʻulaʻula ke hoʻohuli i ka nalowale o ka lohe?
Ua loiloi ʻia ka hopena o ke kukui kokoke-infrared i ka nalowale o ka lohe ma hope o ka lāʻau make chemotherapy. Ua loiloi ʻia ka lohe ma hope o ka hoʻokomo ʻana o ka gentamicin a ma hope o 10 mau lā o ka lāʻau lapaʻau kukui.
Ma ke kiʻi ʻana i nā kiʻi microscope electron, "Ua hoʻonui nui ʻo LLLT i ka helu o nā hunaola lauoho ma nā huli waena a me ke kumu. Ua hoʻomaikaʻi nui ʻia ka lohe ʻana e ka irradiation laser. Ma hope o ka mālama ʻana iā LLLT, ua hoʻomaikaʻi nui ʻia ka paepae lohe a me ka helu o nā hunaola lauoho."
Haʻawina #2: Hiki i ke kukui ʻulaʻula ke hoʻohuli i ka nalowale o ka lohe?
Ma kēia haʻawina, ua hoʻike ʻia nā ʻiole i ka walaʻau nui ma nā pepeiao ʻelua. Ma hope iho, ua hoʻomālamalama ʻia ko lākou mau pepeiao ʻākau me ka mālamalama kokoke i ka infrared no 30 mau minuke i kēlā me kēia lā no 5 mau lā.
Ua hōʻike ke ana ʻana o ka pane o ka lolo auditory i ka wikiwiki o ka hoʻōla ʻana o ka hana auditory i nā hui i mālama ʻia me LLLT i hoʻohālikelike ʻia me ka hui ʻaʻole i mālama ʻia i nā lā 2, 4, 7 a me 14 ma hope o ka hōʻike ʻana i ka walaʻau. Ua hōʻike pū nā nānā ʻana i ke ʻano o ka lolo i kahi kiʻekiʻe loa o ke ola ʻana o nā cell lauoho waho i nā hui LLLT.
I ka ʻimi ʻana i nā hōʻailona o ke kaumaha oxidative a me ka apoptosis i nā cell i mālama ʻole ʻia vs i mālama ʻia, ua ʻike nā mea noiʻi "Ua ʻike ʻia nā immunoreactivities ikaika i loko o nā ʻiʻo pepeiao o loko o ka hui ʻaʻole i mālama ʻia, ʻoiai ua emi kēia mau hōʻailona i ka hui LLLT ma 165mW/cm(2) mana density."
"Hōʻike kā mākou mau ʻike he hopena cytoprotective ko LLLT e kūʻē iā NIHL ma o ka pale ʻana i ka hōʻike ʻana o ka iNOS a me ka apoptosis."
Haʻawina #3: Hiki i ke kukui ʻulaʻula ke hoʻohuli i ka nalowale o ka lohe?
Ma kahi noiʻi i ka makahiki 2012, ua hoʻike ʻia ʻeiwa mau ʻiole i ka walaʻau nui a ua hoʻāʻo ʻia ka hoʻohana ʻana i ke kukui kokoke i ka infrared i ka hoʻōla ʻana o ka lohe. I ka lā ma hope o ka hōʻike ʻana i ka walaʻau nui, ua mālama ʻia nā pepeiao hema o nā ʻiole me ke kukui kokoke i ka infrared no 60 mau minuke no 12 mau lā i ka lālani. ʻAʻole i mālama ʻia nā pepeiao ʻākau a ua manaʻo ʻia ʻo ia ka hui kaohi.
"Ma hope o ka hoʻomālamalama ʻana o ka lā 12, ua haʻahaʻa loa ka paepae lohe no nā pepeiao hema i hoʻohālikelike ʻia me nā pepeiao ʻākau." I ka nānā ʻana me ka hoʻohana ʻana i kahi microscope electron, ʻoi aku ka nui o ka helu o nā hunaola lauoho lohe i loko o nā pepeiao i mālama ʻia ma mua o nā pepeiao i mālama ʻole ʻia.
"Hōʻike kā mākou mau ʻike e hoʻolaha ka irradiation laser haʻahaʻa i ka hoʻōla ʻana o nā paepae lohe ma hope o ka trauma acoustic koʻikoʻi."